One person was killed and another seriously injured in a crash on Interstate 4 in Orlando early Monday morning, police said.

The crash happened at about 3 a.m. in the eastbound lanes of I-4 at South Street.

Investigators said the crash may have been a head-on collision caused by a wrong-way driver.

Eastbound I-4 was shut down for about three hours at Kaley Street.

No other information was immediately released.